Searchable abstracts of presentations at key conferences in endocrinology

ea0090p608 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Intestinimonas butyriciproducens improves glucose metabolism in subjects with obesity and prediabetes: preliminary data from a randomized controlled trial

Antoniotti Valentina , Caputo Marina , TIni Sabrina , Antonioli Alessandro , Daffara Tommaso , De Marchi Silvia , Bona Elisa , Amoruso Angela , Pane Marco , Gul Sahin , Aimaretti Gianluca , Seegers Jos , Prodam Flavia

As the prevalence of type 2 Diabetes Mellitus (T2D) is constantly increasing and the current prevention is not enough, new effective strategies are necessary, in particular in high-risk individuals. Therapeutic microbiology is one of further proposed targets, and, in particular, butyrate-producing bacteria can improve metabolic parameters in obese patients. Our study aims to evaluate the effect of Intestinimonas butyriciproducens as a preventive therapy for T2D in pre...

ea0070oc3.5 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Supplementation with Bifidobacterium breve BR03 and Bifidobacterium breve B632 favoured weight loss and improved insulin metabolism in children and adolescents with obesity in the BIFI-OBESE cross-over, randomized placebo-controlled trial

Solito Arianna , Hasballa Iderina , Calgaro Matteo , Bozzi Cionci Nicole , Ricotti Roberta , Caputo Marina , Genoni Giulia , Monzani Alice , Archero Francesca , Bellone Simonetta , Bona Gianni , Agosti Emanuela , Aimaretti Gianluca , Amoruso Angela , Pane Marco , Vitulo Nicola , Di Gioia Diana , Prodam Flavia

Background: Variations in gut microbiota might impact metabolic functions like caloric intake and energy expenditure leading to body weight excess. Microbiota modulation may be a potential approach for obesity management, especially in subject characterized by specific microbial enterotypes.Objective: We aimed to assess the impact of probiotic treatment in obese children and adolescents, under diet control, on weight loss, glucose, and insulin homeostasi...